4th National Symposium cum Workshop on
"Recent Trends in Structural Bioinformatics and Computer Aided Drug Design"
[SBCADD'2012]
Date of Function:20th –23rd February, 2012
symposium THEme
Human Genome Project is largely complete, so the problem facing by scientists is how to maximize the use of the newly acquired data for improving health care. It is estimated that the number of therapeutic targets available for drug discovery will increase from the current number of 600 to 1000 to perhaps as many as 5000 to 10,000. In addition to the challenges that this number provides to the pharmaceutical industry, there is the issue of sequence variation through Single Nucleotide Polymorphisms (SNPs), some of which may impact upon the way that the body handles drug treatment. This may be due to a direct effect on the binding site of the protein target through non-conservative alterations of the amino acid sequence, or else through indirect effects on drug metabolizing enzymes. In order to meet these challenges, the combination of structural proteomics and computer-aided small molecule design provides opportunities for creating new molecules in silico; these may be designed to bind to selected pharmacogenetic variants of a protein in order to overcome the non-responsiveness of certain patient groups to a particular medicine.
In silico drug discovery methods reduce both time and cost of development of novel drug/lead molecules. Knowledge about the molecule, its interaction with the drug, molecular modeling, and new drug development creates an awareness of the molecule at the organ level and aids in the prevention, diagnosis, and treatment of diseases. Computational tools have the advantage of delivering new lead candidates more quickly and at lower cost. In the 21st century, in silico methods facilitate target identification, structure prediction and lead/drug discovery. The computational methods expect more reliable and expeditious protocols for development of novel ideas, which increase the potential leads. The computer-assisted molecular design has succeeded in the QSAR and protein modeling algorithms to improve activity of lead compounds. Selecting candidates via the described in silico virtual screening, should help to reduce the list of candidate molecules and thereby reduce time and costs significantly.
Tentative speakers
Dr. Arpita Yadav
Institute of Engineering and Technology
Kanpur
Dr. Deva Priyakumar
International Institute of Information Technology
Hyderabad
Dr. K. Gunasekaran
University of Madras
Chennai
Dr. G. Jayaraman
University of Madras
Chennai
Dr. R. Krishna
Pondicherry University
Puducherry
Dr. S. Krishnaswamy
Madurai Kamaraj University
Madurai
Dr. M. Michael Gromiha
Indian Institute of Technology
Chennai
Dr. S. Parthasarthy
Bharthidasan University
Trichy
PARTICIPANTS
Students, Research Scholars, Research Scientists and Faculty members from the Universities, Colleges, Institutes and Industries.
CALL FOR POSTER presentations
The prospective participants are requested to submit the extended abstracts on various aspects on the theme of the symposium (not exceeding 250 words) to the organizing secretary on or before 10th February, 2012. The abstract must be sent to bioinfoau@gmail.com
Contact
Dr. M. Karthikeyan
Organizing Secretary, SBCADD'2012
Department of Bioinformatics
Science Block, 4th Floor
Alagappa University
Karaikudi - 630 004
Tamil Nadu, India. + 91-4565-230725
+91- 4565 225202
bioinfoau@gmail.com
Send your full papers with abstracts to both event email id as well as one CC copy to our email id technicalsymposium@gmail.com for our reference
|
|---|
Share Our valuable information in Face Book -Link Given Below-Share Now
|
Note: When submitting your papers please type subject name as technicalsymposium.com and Your Paper title.
(Because then only all college students&staffs will know our website and our free services.So please type.Thank you)
|
|---|
More Information Please Click here
Source:http://www.bioinfoau.org/sbcadd%272012/index.html